The most common and most likely answer to this crossword clue is the 10 letter word PROFITABLE
I've seen this crossword clue in The Daily Telegraph
P
R
O
F
I
T
A
B
L
E
More clues leading to the result PROFITABLE
- Paying one to follow academic panel
- Lucrative for female, I suggest
- Successful academic, one on board
- Rewarding suitable answer in endless puzzle
- Endless difficulty framing suitable answer that’s useful
- In the Black Isle, head outside for climbing
- “Biography” interrupted by early diet-soda commercial
- Paying for fine inlaid top furniture item
Buddy explains!

The straight part
We know that "Lucrative" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case lucrative = profitable.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does PROFITABLE mean?
PROFITABLE adjective- Producing a profit.