Cryptic crossword clue
Lumpy, bumpy bus route 8

The most common and most likely answer to this crossword clue is the 8 letter word TUBEROUS

T
U
B
E
R
O
U
S

Buddy explains!

The straight part
We know that "Lumpy" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case lumpy = tuberous.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does TUBEROUS mean?

TUBEROUS adjective
  1. Relating to, resembling, or producing tubers
  2. Relating to tuberosities

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