Cryptic crossword clue
Luscious spy I treated with caution 12

The most common and most likely answer to this crossword clue is the 12 letter word SUSPICIOUSLY

I've seen this crossword clue in The Times
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Buddy explains!

The straight part
We know that "with caution" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case with caution = suspiciously.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does SUSPICIOUSLY mean?

SUSPICIOUSLY adverb
  1. (manner) In a way suggesting suspicion.
  2. (manner) In a way that arouses suspicion.
  3. (evaluative) Causing suspicion.
  4. (degree) To a degree that makes one suspect something.

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