The most common and most likely answer to this crossword clue is the 6 letter word VANISH
I've seen this crossword clue in The Guardian
V
A
N
I
S
H
More clues leading to the result VANISH
- Disappear, rather like a motor vehicle?
- Go like a commercial vehicle?
- Go like a trading vehicle?
- Vehicle is hard to make disappear
- Put on a coat, run away, and disappear
- Gloss right away to fade
- Lustre not right — get lost
- Run away from seal and disappear
- Go like an old Dormobile?
- HungAry? Camper maybe is heading for that, faint as before
Buddy explains!

The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does VANISH mean?
VANISH noun- The brief terminal part of a vowel or vocal element, differing more or less in quality from the main part.
- A magic trick in which something seems to disappear.
- To become invisible or to move out of view unnoticed.
- To become equal to zero.
- To disappear; to kidnap