The most common and most likely answer to this crossword clue is the 6 letter word VERONA
I've seen this crossword clue in The Daily Telegraph
V
E
R
O
N
A
More clues leading to the result VERONA
- Italian city museum enthralling English chap
- Some turning up in Slovenian or even Italian city
- Place with theatrical gentlemen getting on interrupting woman
- City functioning within very short period
- Transported by lover, on about Italian city
- Italian city in Milano revered after revolution?
- Lynn, perhaps, banking on Italian city
- Clergyman gets uppity about a gentlemen’s residence
- Girl carrying on in Italian city
- A refusal by cleric to go round Italian city
Buddy explains!

The straight part
We know that "Italian city" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case italian city = verona.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.