Cryptic crossword clue
M or F? Put out to allow for one of six 9

The most common and most likely answer to this crossword clue is the 9 letter word SEXTUPLET

S
E
X
T
U
P
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E
T

Buddy explains!

The straight part
We know that "one of six" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case one of six = sextuplet.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does SEXTUPLET mean?

SEXTUPLET noun
  1. A group of six objects.
  2. One of a group of six persons or animals born from the same mother during the same birth.
  3. A group of six notes played in the time of four.

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