Cryptic crossword clue
Macbeth might say “It’s a gas!” 7

The most common and most likely answer to this crossword clue is the 7 letter word METHANE

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The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does METHANE mean?

METHANE noun
  1. The simplest aliphatic hydrocarbon, CH₄, being a constituent of natural gas, and one of the most abundant greenhouse gases.
  2. Any of very many derivatives of methane.

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