Cryptic crossword clue
Macho man unable to open desk 4

The most common and most likely answer to this crossword clue is the 4 letter word AMBO

A
M
B
O


Buddy explains!

The straight part
We know that "desk" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case desk = ambo.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does AMBO mean?

AMBO noun
  1. A raised platform in an early Christian church, as well as in the Eastern Orthodox, Oriental Orthodox, and Eastern Catholic churches.
  2. A stationary podium used for readings and homilies.
AMBO noun
  1. An ambulance driver.
  2. An ambulance.

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