Cryptic crossword clue
Mad chemist raging and discordant 10

The most common and most likely answer to this crossword clue is the 10 letter word MISMATCHED

I've seen this crossword clue in Independent
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Buddy explains!

The straight part
We know that "discordant" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case discordant = mismatched.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does MISMATCHED mean?

MISMATCHED verb
  1. To match unsuitably; to fail to match
MISMATCHED adjective
  1. Unsuitably matched; ill joined.

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