Cryptic crossword clue
Mad mother turned murderer 6

The most common and most likely answer to this crossword clue is the 6 letter word MANIAC

I've seen this crossword clue in The Guardian
M
A
N
I
A
C


Buddy explains!

The straight part
We know that "Mad" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case mad = maniac.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does MANIAC mean?

MANIAC noun
  1. An insane person, especially one who suffers from a mania.
  2. A fanatic, a person with an obsession.

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