The most common and most likely answer to this crossword clue is the 10 letter word SENSITISED
I've seen this crossword clue in Independent
S
E
N
S
I
T
I
S
E
D
More clues leading to the result SENSITISED
Buddy explains!

The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does SENSITISED mean?
SENSITISED verb- To make (someone or something) sensitive or responsive to certain stimuli.
- To make (someone) increasingly aware of, in a concerned or sensitive way.
- To render capable of being acted on by actinic rays of light.
- Made sensitive, especially to some specific agent.