The most common and most likely answer to this crossword clue is the 6 letter word MANIAC
I've seen this crossword clue in The Times
M
A
N
I
A
C
More clues leading to the result MANIAC
- Crazy graduate turned murderer
- Madman trapping bird in raincoat
- Fiend who first killed a maiden from the east
- PC arrests a Northern Irish nutter
- . Chap with current account? He’s lost it
- Person in charge of restraining a madman
- Deranged piece by Independent
- Mad mother turned murderer
- Massachusetts’ murderer brought back, a deranged person
- Chap put on island about turned loony
Buddy explains!

The straight part
We know that "Madman" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case madman = maniac.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does MANIAC mean?
MANIAC noun- An insane person, especially one who suffers from a mania.
- A fanatic, a person with an obsession.