The most common and most likely answer to this crossword clue is the 10 letter word DEPRESSION
D
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P
R
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S
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I
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N
More clues leading to the result DEPRESSION
- Hollow liquid dispenser with nothing in
- Pit of despair
- Prof passes round English papers – I slump
- Getting upset my boss and I keep going over 26
- Misery often associated with the deep Atlantic
- Slump causing gloom
- Black dog bowl
- It causes rough weather and loss of trade
- Open dress I fancy showing dimple
- Player down before media faction released information about low spirits
Buddy explains!

The straight part
We know that "in dumps" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case in dumps = depression.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does DEPRESSION mean?
DEPRESSION noun- In psychotherapy and psychiatry, a state of mind producing serious, long-term lowering of enjoyment of life or inability to visualize a happy future.
- An area that is lower in topography than its surroundings.
- In psychotherapy and psychiatry, a period of unhappiness or low morale which lasts longer than several weeks and may include ideation of self-inflicted injury or suicide.
- An area of lowered air pressure that generally brings moist weather, sometimes promoting hurricanes and tornadoes.
- A period of major economic contraction.
- Four consecutive quarters of negative, real GDP growth. See NBER.
- The act of lowering or pressing something down.
- A lowering, in particular a reduction in a particular biological variable or the function of an organ, in contrast to elevation.