The most common and most likely answer to this crossword clue is the 8 letter word ARTERIAL
I've seen this crossword clue in The Times
A
R
T
E
R
I
A
L
More clues leading to the result ARTERIAL
- Main channel's receiver concealing coating of rust
- Antenna limits radio telephony along major roads
- Right time to burst above the ground, like a tube
- Like major thoroughfare in which a trailer gets wrecked
- Hesitation in a complex trial of major routes
- Couple of errors in a complex trial of major routes
- A collision in trailer of vital pump supplier?
- Main article on damaged trailer
- Main antenna covering East and West Timor
- Perhaps a main road featuring in, say, movie episode after commencement
Buddy explains!
The straight part
We know that "Main channel's" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case main channel's = arterial.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does ARTERIAL mean?
ARTERIAL noun- A through road.
- Of or relating to an artery.
- (of a route, road or street) Major, important.