Cryptic crossword clue
Main chant as cyclist retires — hard to puncture two tyres 2-2-2

The most common and most likely answer to this crossword clue is the 8 letter word YO-HO-HO

I've seen this crossword clue in The Guardian
Y
O
-
H
O
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H
O

Buddy explains!

The straight part
We know that "Main chant" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case main chant = yo-ho-ho.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does YO-HO-HO mean?

YO-HO-HO interjection
  1. A cry associated with pirates and seafaring, originally a repetitive chant intended to synchronize workers performing some collective physical labour, such as hauling on a rope.

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