Cryptic crossword clue
Main growths in college and primary school heads 6

The most common and most likely answer to this crossword clue is the 6 letter word POLYPS

I've seen this crossword clue in Financial Times
P
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P
S


Buddy explains!

The straight part
We know that "Main growths" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case main growths = polyps.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does POLYPS mean?

POLYPS noun
  1. An abnormal growth protruding from a mucous membrane
  2. A cylindrical coelenterate, such as the hydra, having a mouth surrounded with tentacles

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