Cryptic crossword clue
Majority of L-dopa queries becoming more puzzling 7

The most common and most likely answer to this crossword clue is the 7 letter word OPAQUER

O
P
A
Q
U
E
R

Buddy explains!

The straight part
We know that "more puzzling" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case more puzzling = opaquer.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does OPAQUER mean?

OPAQUER adjective
  1. Neither reflecting nor emitting light.
  2. Allowing little light to pass through, not translucent or transparent.
  3. Unclear, unintelligible, hard to get or explain the meaning of
  4. Obtuse, stupid.
  5. Describes a type for which higher-level callers have no knowledge of data values or their representations; all operations are carried out by the type's defined abstract operators.

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