Cryptic crossword clue
Major‘s really sick 8

The most common and most likely answer to this crossword clue is the 8 letter word CRITICAL

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Buddy explains!

The straight part
We know that "Major/really sick" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case major/really sick = critical.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does CRITICAL mean?

CRITICAL noun
  1. A critical value, factor, etc.
  2. In breakdancing, a kind of airflare move in which the dancer hops from one hand to the other.
CRITICAL adjective
  1. Inclined to find fault or criticize
  2. Pertaining to, or indicating, a crisis or turning point.
  3. Extremely important.
  4. Relating to criticism or careful analysis, such as literary or film criticism.
  5. Of a patient condition involving unstable vital signs and a prognosis that predicts the condition could worsen; or, a patient condition that requires urgent treatment in an intensive care or critical care medical facility.
  6. Likely to go out of control if disturbed, that is, opposite of stable.
  7. Of the point (in temperature, reagent concentration etc.) where a nuclear or chemical reaction becomes self-sustaining.
  8. (physics) Of a temperature that is equal to the temperature of the critical point of a substance, i.e. the temperature above which the substance cannot be liquefied.

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