The most common and most likely answer to this crossword clue is the 3 plus 3 plus 3 letter word CUT AND RUN
I've seen this crossword clue in The Guardian
C
U
T
A
N
D
R
U
N
More clues leading to the result CUT AND RUN
- Clear out of joint with ladder
- Escape quickly after seeing copper close to flat with ladder
- Stop filming with single light out
- What a batsman might do: leave
- Clip plus last bolt
- Make a break for it, when copper on beat’s briefly tipsy
- Escape copper at early closing boozer, hide inside
- What a batsman might do in a hurry?
- What a buttonholed listener might do...
- Split commission, added extra
Buddy explains!

The straight part
We know that "Make a break for it" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case make a break for it = cut and run.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.