The most common and most likely answer to this crossword clue is the 9 letter word DELOUSING
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More clues leading to the result DELOUSING
Buddy explains!

The straight part
We know that "Make a cartoon" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case make a cartoon = delousing.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does DELOUSING mean?
DELOUSING verb- To remove lice from.
- To apply insecticides or insect repellents to, in order to be sure that no lice or other parasites are present.
- To remove malicious software, such as viruses, trojans, spyware, or worms, from.