Cryptic crossword clue
Make lean daughter grilled feta 5

The most common and most likely answer to this crossword clue is the 5 letter word DEFAT

I've seen this crossword clue in The Guardian
D
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The straight part
We know that "Make lean" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case make lean = defat.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does DEFAT mean?

DEFAT verb
  1. To remove fat from a material, especially by the use of solvents

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