The most common and most likely answer to this crossword clue is the 4 letter word REDO
I've seen this crossword clue in The Guardian
R
E
D
O
More clues leading to the result REDO
- Catholic excused from belief to try again
- Repeat one note after another
- Model again getting embarrassed over nothing
- Try again to get out of fire door
- Revolutionary circle to form again
- Make significant changes out of boredom
- First two notes in wrong order? Try again
- Embarrassed by over, have a second try
- Once more, make love after wine
- Regularly seen Friends on repeat
Buddy explains!
The straight part
We know that "Make significant changes" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case make significant changes = redo.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does REDO mean?
REDO noun- A repeated action; a doing again, refurbishment, etc.
- To do again.