The most common and most likely answer to this crossword clue is the 10 letter word FORCE-FEED
I've seen this crossword clue in The Times
F
O
R
C
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F
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Buddy explains!

The straight part
We know that "Make stuff" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case make stuff = force-feed.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does FORCE-FEED mean?
FORCE-FEED verb- To force a person or animal to ingest food, for example by stuffing food down the throat, or using a tube passed into the stomach.
- More broadly, also referring to forcing the drinking of a beverage or other liquid
- To force someone to take in information or accept an ideology.