The most common and most likely answer to this crossword clue is the 5 letter word PINOT
I've seen this crossword clue in The Times
P
I
N
O
T
More clues leading to the result PINOT
Buddy explains!

The straight part
We know that "Maker of wine" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case maker of wine = pinot.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does PINOT mean?
PINOT noun- Any of several grape varieties grown in Europe and North America.
- (by extension) Any of several wines made from these grapes.