Cryptic crossword clue
Makes peer and earl run away from home, twice

The most common and most likely answer to this crossword clue is the 7 letter word EQUATES

E
Q
U
A
T
E
S


Buddy explains!

The straight part
We know that "Makes peer" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case makes peer = equates.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does EQUATES mean?

EQUATES noun
  1. A statement in assembly language that defines a symbol having a particular value.
EQUATES verb
  1. To consider equal or equivalent.
  2. To set as equal.

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