Cryptic crossword clue
Makes ready for use again in harder, heartless round 6

The most common and most likely answer to this crossword clue is the 6 letter word REFITS

I've seen this crossword clue in The Guardian
R
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Buddy explains!

The straight part
We know that "Makes ready for use again" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case makes ready for use again = refits.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does REFITS mean?

REFITS noun
  1. The process of having something fitted again, repaired or restored.

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