Cryptic crossword clue
Making an enemy of a right awful giant 10

The most common and most likely answer to this crossword clue is the 10 letter word ALIENATING

I've seen this crossword clue in The Daily Telegraph
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Buddy explains!

The straight part
We know that "Making an enemy of" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case making an enemy of = alienating.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does ALIENATING mean?

ALIENATING verb
  1. To convey or transfer to another, as title, property, or right; to part voluntarily with ownership of.
  2. To estrange; to withdraw affections or attention from; to make indifferent or averse, where love or friendship before subsisted.
ALIENATING adjective
  1. Tending to alienate.

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