Cryptic crossword clue
Making certain squeal taking remedy end first 8

The most common and most likely answer to this crossword clue is the 8 letter word SECURING

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The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does SECURING mean?

SECURING verb
  1. To make safe; to relieve from apprehensions of, or exposure to, danger; to guard; to protect.
  2. To put beyond hazard of losing or of not receiving; to make certain; to assure; frequently with against or from, or formerly with of.
  3. To make fast; to close or confine effectually; to render incapable of getting loose or escaping.
  4. To get possession of; to make oneself secure of; to acquire certainly.
  5. To plight or pledge.

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