Cryptic crossword clue
Making small cocktail of martini, using bottled Asti at the end 13

The most common and most likely answer to this crossword clue is the 13 letter word MINIATURISING

M
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Buddy explains!

The straight part
We know that "Making small" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case making small = miniaturising.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does MINIATURISING mean?

MINIATURISING verb
  1. To design or construct something on a miniature scale.

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