Cryptic crossword clue
Making the most of wise words, I celebrate 10

The most common and most likely answer to this crossword clue is the 10 letter word MAXIMISING

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Buddy explains!

The straight part
We know that "Making the most of" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case making the most of = maximising.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does MAXIMISING mean?

MAXIMISING verb
  1. To make as large as possible
  2. To expand (a window) to fill the main display area

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