Cryptic crossword clue
Making uncomfortable, running off to gather energy and velocity 9

The most common and most likely answer to this crossword clue is the 9 letter word UNNERVING

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Buddy explains!

The straight part
We know that "Making uncomfortable" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case making uncomfortable = unnerving.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does UNNERVING mean?

UNNERVING verb
  1. To deprive of nerve, force, or strength; to weaken; to enfeeble.
  2. To make somebody nervous, upset, alarm, shake the resolve of.

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