Cryptic crossword clue
Man goes after fourth part of play with genuine effort 8

The most common and most likely answer to this crossword clue is the 8 letter word ACTIVELY

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Buddy explains!

The straight part
We know that "with genuine effort" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case with genuine effort = actively.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does ACTIVELY mean?

ACTIVELY adverb
  1. In an active manner.
  2. (grammar) In the active form; not passive.

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