Cryptic crossword clue
Man on train’s an old friend 12

The most common and most likely answer to this crossword clue is the 12 letter word SCHOOLFELLOW

I've seen this crossword clue in The Guardian
S
C
H
O
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L
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W

Buddy explains!

The straight part
We know that "old friend" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case old friend = schoolfellow.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does SCHOOLFELLOW mean?

SCHOOLFELLOW noun
  1. A person who was a fellow attendee at one's school.

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