Cryptic crossword clue
Mark’s swapping sides for 27

The most common and most likely answer to this crossword clue is the 5 letter word FLANK

I've seen this crossword clue in Independent
F
L
A
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K

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The straight part
We know that "27" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case 27 = flank.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does FLANK mean?

FLANK noun
  1. The flesh between the last rib and the hip; the side.
  2. A cut of meat from the flank of an animal.
  3. The extreme left or right edge of a military formation, army etc.
  4. The sides of a bastion perpendicular to the wall from which the bastion projects.
  5. The side of something, in general senses.
  6. The outermost strip of a road.
  7. The wing, one side of the pitch.
  8. That part of the acting surface of a gear wheel tooth that lies within the pitch line.
FLANK verb
  1. To attack the flank(s) of.
  2. To defend the flank(s) of.
  3. To place to the side(s) of.
  4. To be placed to the side(s) of something (usually in terms of two objects, one on each side).
FLANK adjective
  1. (of speed) Maximum. Historically faster than full speed (the most a vessel can sustain without excessive engine wear or risk of damage), now frequently used interchangeably. Typically used in an emergency or during an attack.

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