Cryptic crossword clue
Maternal grandmother inhaling Italy’s noxious air? 6

The most common and most likely answer to this crossword clue is the 6 letter word MIASMA

I've seen this crossword clue in The Guardian
M
I
A
S
M
A


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The cryptic/wordplay part
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What does MIASMA mean?

MIASMA noun
  1. A noxious atmosphere or influence.
  2. A noxious atmosphere or emanation once thought to originate from swamps and waste, and to cause disease.

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