The most common and most likely answer to this crossword clue is the 11 letter word DETERMINATE
I've seen this crossword clue in The Daily Telegraph
D
E
T
E
R
M
I
N
A
T
E
Buddy explains!
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does DETERMINATE mean?
DETERMINATE noun- A single state of a particular determinable attribute.
- Distinct, clearly defined.
- Fixed, set, unvarying.
- Of growth: ending once a genetically predetermined structure has formed.
- Conclusive; decisive; positive.
- Determined or resolved upon.
- Of determined purpose; resolute.
- To bring to an end; to determine.