Cryptic crossword clue
Maybe possessed lake south of rocky Macedonia 10

The most common and most likely answer to this crossword clue is the 10 letter word DEMONIACAL

I've seen this crossword clue in The Guardian
D
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Buddy explains!

The straight part
We know that "Maybe possessed" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case maybe possessed = demoniacal.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does DEMONIACAL mean?

DEMONIACAL adjective
  1. Pertaining to, characteristic of, or produced by a demon or evil spirit; devilish or fiendish.

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