Cryptic crossword clue
MD treated Sue in exercises not properly appreciated 14

The most common and most likely answer to this crossword clue is the 14 letter word UNDERESTIMATED

I've seen this crossword clue in The Times
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Buddy explains!

The straight part
We know that "not properly appreciated" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case not properly appreciated = underestimated.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does UNDERESTIMATED mean?

UNDERESTIMATED verb
  1. To perceive (someone or something) as having a lower value, quantity, worth, etc., than what he/she/it actually has.

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