The most common and most likely answer to this crossword clue is the 6 plus 6 plus 7 letter word SEVERN VALLEY RAILWAY
I've seen this crossword clue in The Guardian
S
E
V
E
R
N
V
A
L
L
E
Y
R
A
I
L
W
A
Y
Buddy explains!
The straight part
We know that "Meandering line" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case meandering line = severn valley railway.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.