Cryptic crossword clue
Measure the concentration of a solution as solvent at the bottom is replaced with new inorganic compound 7

The most common and most likely answer to this crossword clue is the 7 letter word NITRATE

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Buddy explains!

The straight part
We know that "inorganic compound" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case inorganic compound = nitrate.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does NITRATE mean?

NITRATE noun
  1. Any salt or ester of nitric acid.
NITRATE verb
  1. To treat, or react, with nitric acid or a nitrate

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