The most common and most likely answer to this crossword clue is the 11 letter word PASTY-FACED
I've seen this crossword clue in The Times
P
A
S
T
Y
-
F
A
C
E
D
Buddy explains!
The straight part
We know that "looking anaemic" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case looking anaemic = pasty-faced.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.