Cryptic crossword clue
Medical professional R[OASTED] on radio too wise to swallow line with deadpan sarcasm 5

The most common and most likely answer to this crossword clue is the 5 letter word DRYLY

D
R
Y
L
Y

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The straight part
We know that "with deadpan sarcasm" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case with deadpan sarcasm = dryly.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does DRYLY mean?

DRYLY adverb
  1. In a dry manner.

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