Cryptic crossword clue
Medicinal application I smear after start of nettle-rash 6

The most common and most likely answer to this crossword clue is the 7 letter word NIM-OIL

N
I
M
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O
I
L

Buddy explains!

The straight part
We know that "Medicinal application" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case medicinal application = nim-oil.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

Crossword Answer definitions


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