Cryptic crossword clue
Member of family carries nothing around? Big van can do that job 10

The most common and most likely answer to this crossword clue is the 10 letter word RELOCATION

I've seen this crossword clue in The Daily Telegraph
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Buddy explains!

The straight part
We know that "Big van can do that job" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case big van can do that job = relocation.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does RELOCATION mean?

RELOCATION noun
  1. The act of moving from one place to another.
  2. Renewal of a lease.
  3. The assigning of addresses to variables either at linkage editing, or at run time

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