Cryptic crossword clue
Membranesin a mess a thousand

The most common and most likely answer to this crossword clue is the 5 letter word AMNIA

I've seen this crossword clue in The Guardian
A
M
N
I
A


Buddy explains!

The straight part
We know that "Membranes" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case membranes = amnia.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does AMNIA mean?

AMNIA noun
  1. The innermost membrane of the fetal membranes of reptiles, birds, and mammals; the sac in which the embryo is suspended.

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