Cryptic crossword clue
Mentally disturbed people appear in film with this cast, oddly enough 10

The most common and most likely answer to this crossword clue is the 10 letter word PSYCHOTICS

I've seen this crossword clue in Financial Times
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Buddy explains!

The straight part
We know that "Mentally disturbed people" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case mentally disturbed people = psychotics.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does PSYCHOTICS mean?

PSYCHOTICS noun
  1. A person affected by psychosis.

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