Cryptic crossword clue
Mescal made skipping maidens go up the wall 8

The most common and most likely answer to this crossword clue is the 8 letter word ESCALADE

I've seen this crossword clue in The Guardian
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Buddy explains!

The straight part
We know that "go up the wall" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case go up the wall = escalade.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does ESCALADE mean?

ESCALADE noun
  1. An act of scaling walls or fortifications
ESCALADE verb
  1. To scale the walls of a fortification.

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