Cryptic crossword clue
Minute edited from chirpy daytime broadcast is source of internal discomfort 12

The most common and most likely answer to this crossword clue is the 12 letter word HYPERACIDITY

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Buddy explains!

The straight part
We know that "source of internal discomfort" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case source of internal discomfort = hyperacidity.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does HYPERACIDITY mean?

HYPERACIDITY noun
  1. The condition of being excessively acidic

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