Cryptic crossword clue
Miracle Anselm bottles to set free from guilt

The most common and most likely answer to this crossword clue is the 7 letter word CLEANSE

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The straight part
We know that "to set free from guilt" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case to set free from guilt = cleanse.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does CLEANSE mean?

CLEANSE noun
  1. An act of cleansing; a purification.
CLEANSE verb
  1. To free from dirt; to clean, to purify.
  2. To spiritually purify; to free from guilt or sin; to purge.

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