Cryptic crossword clue
Mistrusts the French leaving for a short time during game of tennis 6

The most common and most likely answer to this crossword clue is the 6 letter word DOUBTS

I've seen this crossword clue in The Guardian
D
O
U
B
T
S

Buddy explains!

The straight part
We know that "Mistrusts" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case mistrusts = doubts.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does DOUBTS mean?

DOUBTS noun
  1. Disbelief or uncertainty (about something); a particular instance of such disbelief or uncertainty.
  2. A point of uncertainty; a query.
DOUBTS verb
  1. To be undecided about; to lack confidence in; to disbelieve, to question.
  2. To harbour suspicion about; suspect.
  3. To anticipate with dread or fear; to apprehend.
  4. To fill with fear; to affright.
  5. To dread, to fear.

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